ABAKAVIR (Abacavir).

     (1S, 4R) -4-[2-Amino-6- (tsiklopropilamino) -9 H purin-9- d] -2 - tsiklopenten-1- methanol succinate.

     Synonym : Ziagen, Ziagen.

     Ingibiruet reverse transcriptase of HIV-1 and VICH-2.

     When administered quickly and almost completely absorbed, bioavailability of about 83%, S-max 1-1,5 h, T? - 1.5 h; biotransformation are in the liver, kidneys predominantly displayed.

     Applied in the treatment of HIV infection.

     Assign the interior of 0.3 g adults, children 8 mg / kg 2 times a day.

     Possible side effects : diarrhoeal phenomenon, disruption of the liver and pancreas, molochnokisly disorders.

     Contraindications : breast-feeding.

     Method of issuance : pills to 0.3 g (N. 10); 2% solution for the reception inside the bottles in 240 ml.

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines