MEFENAMINOVAYA ACID (Acidum mephenamicum).

     N - (2, 3-Dimetilfenil) anthranilic acid.

     Synonyms : Acidum mefenamicum, Coslan, Lysalgo, Mefenamic acid, Parkemed, Ponstan, Ponstel, Ponstyl, Pontal, Tanston and others.

     The crystalline powder colour white. Almost nerastvorim in the water, little is soluble in alcohol.

     Mefenamovaya acid is a derivative of anthranilic acid, which has elements of the structural similarities with salicylic acid and its derivatives, used as an anti funds. She has analgeziruyuschey, analgesic and antiinflammatory activity, both antiinflammatory activity ahead of musk. On analgeziruyuschey activity mefenamovaya acid equivalent butadionu and beyond musk, and analgesic action is these drugs.

     On mechanism of acid mefenamovaya close to other steroidal antiinflammatory agents. On ability to oppress biosynthesis prostaglandines took intersection butadionom and indometacin.

     Applied mefenamovuyu acid with rheumatoid arthritis, non-infectious polyarthritis, arthralgia and muscular pain, disease, with headache and toothache, etc. and as with the various anti frenzied state.

     Assign inside (after eating) for adults 0.5 g 3 - 4 times a day. If necessary, and good endurance increase to a maximum daily dose of 3 g, and after a therapeutic effect to reduce the dose of 1 g per day. Children between the ages of 5 and 10 years appoint 0.25 g 3 - 4 times a day, over 10 years - 0.3 g 3 - 4 times a day.

     The length of treatment depends on the case and endurance drug; Treatment is usually continued 20 to 45 days (if necessary until 2 months).

     The drug is usually well (sometimes he was appointed in poor Portability salitsilatov), but it can cause nausea, abdominal pain, diarrhea. To prevent these phenomena taken after food preparation. Recommended zapivat milk tablets. In some cases, possible allergic phenomena (skin itch, rash).

     Mefenamovaya acid is not suitable for stomach ulcers and gastrointestinal cancer and inflammatory diseases zheludochnokishechnogo tract.

     There is a need to be cautious about the appointment of a drug to patients with diseases of the blood and kidneys.

     Product type : yellow, white tablets of 0.25; 0.35 and 0.5 g in a package of 50 pieces.

     Storage : List B. In dry, the dark spot.

     Overseas (India) issued a combined drug-pill <<Lanagesik>> (Lanagesic) containing 0.25 g mefenamovoy acid and 0.5 grams of paracetamol.

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