ALUMINIUM GIDROOKIS (Aluminii hydroxydum).
Synonyms : A luminium hydroxydatum, A1uminium is hydroxyd
Amorphous loose white powder in the water almost nerastvorim and can form a gel; Soluble heated in the diluted acid and caustic alkali solutions.
Has antatsidnymi, absorbent and coating properties
The drug neutralizes hydrochloric acid (HCl) (1 g neutralizes approximately 250 ml 0,1 said. The solution of hydrochloric acid) with the formation of aluminium chloride and water; PH gastric juice gradually increased to 3, May 4, 5 and remained at that level in the next few hours. In this sense, not only decreasing pH acidity gastric juice, they are oppressed his pepticheskaya (proteolytic) activity. In alkaline content bowel aluminum chloride form insoluble (and nevsasyvayuschiesya) aluminum compounds (phosphate, etc.) and chlorine ions. Reabsorbiruyutsya chlorine ions, so alkaloz not progressing.
Inside designate aluminium hydroxide at high pH digestive juices, stomach ulcers and duodenal ulcers, acute and chronic gastritis giperatsidnyh and food poisoning.
Inside appointed as suspensions (4%) in water, usually 1 - 2 tea spoons 4 to 6 times a day.
Currently, the wider use of other drugs containing aluminium, including the combined dosage forms (see Almagel, Gastal, etc.).
When using aluminium hydroxide may develop constipation. In conjunction with magnesium oxide (see Gastal) antatsidny effect of increases and decreases the possibility of constipation.
Because aluminum hydroxide that binds phosphate, and delaying their intake of the gastrointestinal tract, it is used in giperfosfatemii accompanying renal failure. However, there are indications that when expressed as a violation of kidney drugs aluminium not receive.
Aluminum hydroxide is sometimes used as a binder of External with skin diseases.
Product : powder.
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