AMBEN (Ambenum). [Ambenom in foreign literature also called para-aminobenzoynuyu acid, which antifibrinoliticheskoy activity is not (see Novokain).] . parameters (Aminometil) - benzoic acid.
Synonyms : Pamba, Gumbix, R amba, Styptopur.
The white crystalline powder and odourless. Poor slowly dissolves in the water.
Antifibrinoliticheskoe funds. Arrangement and the mechanism of close to aminokapronovoy acid; Oppressing fibrinolysis by competitive enzyme plazminogenaktiviruyuschego braking and oppression plazmina education.
Compared with the acid aminokapronovoy more active.
Applied to stop bleeding in surgical intervention and various pathologic conditions, a raise fibrinoliticheskoy activity of blood and tissue, and haemorrhagic diathesis trombotsitopenicheskogo origin.
Enter struyno drug intravenously in doses of 50, 100 mg (5 - 10 mL 1% solution). If necessary, re-enter at intervals of not less than 4 hours Introduction ambena can be combined with the infusion of glucose solution, giprolizatov, protivoshokovyh liquids.
In more severe fibrinolysis designate fibrin (see), controlling blood fibrinoliticheskuyu activity and the content of fibrinogena.
The maximum single dose of drug, 100 mg (10 mL 1% solution). The total daily dose and duration of treatment depended on the course of the disease.
Indications are the same as for the acid aminokapronovoy.
Product : 1% solution in ampoules to 5 ml (50 mg).
Storage : in the dark spot.
A sponge gemostaticheskaya with ambenom (Spongia haemostatica cum mbeno A) containing human blood plasma, amben and calcium chloride. It is a dry, porous, gigroskopicheskoe substance white with a yellowish sheen. Local applied to stop bleeding.
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