AMILORID (Amiloridum) *.

     N-Amidino-3, 5-diamino-6- hlorpirazinkarboksamida hydrochloride.

     C inonimy : Amilorid hydrochlorid, Amipramidine, Amiprazid, Arumil, Cofectril, Diursan, Guanamprazine, Medamor, Midamor, Modamide, Nilurid, Pandiuren and others.

     There are mainly distal portion of kidney channel increased allocation of sodium and chlorine ions and reduces the allocation of potassium ions. Has diuretichesky effect, but less strong than tiazidovye Diuretics.

     Activity begins at 2 h after administration of inwards and lasts up to 24 hours

     Applied mainly in combination with other diuretikami (dihlotiazidom etc.). Amiloride diureticheskoe heightens the effect and reduces the risk gipokaliemii.

     Assign inside for 2, 5 - 5, 0-20.0 mg per day (no more than 40 mg per day).

     Product : pills to 0,025 g (2, 5 mg) and 0,005 g (5 mg).

     The so-called "Moduretik" (name drug firms' ME RCK & SO. , IN C. "R and hw how, N. J., U. S. A.) (Mo duretic) A drug-combination tablet containing 50 mg gidrohlortiazida (dihlotiazida) amilorida and 5 mg. Is 1 - 2 tablets 4 times a day.

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