AMINOGLUTETIMID (Aminoglutethimide). 3-Etil-3- (para-aminofenil) 2, 6-dioksopiperidin.

     Synonyms : Mamomit, Orimeten, Xu tadren, E lipten, amomit M, O rimeten.

     On chemical structure is similar aminoglutethimide with sleeping pills and drug Qlyutetimid convulsants (synonyms : Noksiron-N ohu of r n, Doriden -Doriden). Is there only in the amino phenyl nucleus.

     Aminoglutethimide also has protivosudorozhnoy activity, but it has attracted the most interest, as a fusion inhibitor adrenokortikosteroidov, primarily hydrocortisone. It also inhibits the biosynthesis of estrogen.

     Applied aminoglutethimide with Itsenko syndrome, and for Kushinga <pharmacological adrenalektomii> adrenal cortex in tumors (see Hloditan). When applied to breast cancer.

     Assign inside of 0.25 g 2 - 4 times a day. Is day long (depending on the course of the disease).

     The drug is usually well. Sometimes there allergic skin reactions, swelling Kvinke.

     Product : pills to 0.25 g.

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