BAKLOFEN (Baclofen) *. 4-Amino-3- (para-chlorophenyl) - Oil acid

     Synonyms : Lioresal, Baclon, Gabalon, Lioresal, Spastin.

     The structure is similar to Baclofen derivative g-aminomaslyanoy acid aminolonom fenibutom and (see) from the latter distinguished by the chlorine atom in the parameters of the phenyl nucleus.

     Pharmacological properties baklofena other than fenibuta and other neuroprotective drugs (see). He is GAMK- B receptor agonist, but mainly due to his antispasticheskoe - pharmacological effect. It oppresses and emerging spinal reflexes, reduces muscle tension, klonus. Has also analgesic effect.

     Baclofen applied to reduce Spasticity with scattered sclerosis and other Spasticity (mainly spinal origin), but not in patients' muscle rigidity parkinsonizmom.

     Assign Baclofen inside (in food), from 5 mg three times a day, then increase the dose (every 3 days to 5 mg three times a day) to a maximum daily dose of 60-75 mg. Remove drug should be gradually.

     Before baklofena possible nausea, vomiting, dizziness. Like other muscle Judge, it may disrupt the normal course of the ability to fight.

     Contraindications : psychosis, epilepsy, Parkinson's disease. Caution is needed in violation of kidney function.

     Product : pills for 10 and 25 mg in a package of 50 pieces.

     Storage : List B.

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