Kaltsitriol (calcitriol)


KALTSITRIOL (Calcitriol).
     (1? 3? , 5Z, 7E) -9,10 - Sekoholesta-5, 7.10 (19) - triene-1, 3.25 - triol.
     Synonym : Rokaltrol, Rocaltrol.
     The white crystalline powder. The relatively soluble in water, soluble in organic solvents.
     The synthetic analogue of the active metabolite of vitamin D (holekaltsiferola).
     Has calcium absorption in the gut, regulates bone mineralization, stimulates osteoclasts.
     Applied with rickets, menopause osteoporosis, and kidney osteodystrophies genesis (of renal failure, including against the backdrop of hemodialysis) and gipoparatireoze (aftercare and idiopathic).
     Assign into adults, starting with 0.25 µ g / day, as appropriate daily dose increase over 2-4 weeks to 0.25 mg to 0,5-1 mg and above : with menopause osteoporosis apply to 0.25 µ g 2 times day.
     Children appoint 0,01-0,1 ug / kg.
     Possible side effects : giperkaltsiemiya, headache, vomiting, constipation, sensitivity disorder, fever, thirst, poliuriya, dehydration, lethargy, stunted growth, urinary tract infection routes.
     The drug is contraindicated in giperkaltsiemii.
     After 1, 3 and 6 months and then at intervals of six months to determine the content of calcium in the blood.
     Product : Capsule for 0.25 and 0.5 µ g (N. 30, 100).
     Storage : List B.

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