TSEFTRIAKSON (Ceftriaxon) *.

     Tsefalosporinovy antibiotic third generation. According to the chemical structure similar to tsefotaksimu. Issued in the form of sodium salt.

     Synonyms: Longatsef, Rotsefin, Betasporin, Cefadrox, Cefadroxil, Cefamox, Ceftriakson, Duracef, Longacef, Rocephin, Ultracef and others.

     Like tsefotaksimu not absorbed from the gastrointestinal tract; Applied intramuscularly and intravenously. After vnutrimyshechnogo a peak concentration in blood plasma was after 1, 5 hours The product is the long-term remains in the body. Minimum anti concentrations detected in the blood within 24 hours and more.

     The product is well into the body, the body fluid (peritoneal, pleural, rabies, sinovialnuyu) in the bone tissue.

     Provided (50%) in the kidneys active form within 48 hours When kidney failure allocation slowing. Partly derived from export.

     Indications for use ceftriaxone in the same indication to the other tsefalosporinov third generation (see Tsefotaksim).

     The main differences stem ceftriaxone its pharmacokinetic characteristics: the slow down of the body (this allows you to enter his usual one every day, and in severe cases, two times a day), a wide spectrum of (used in the resistance of microorganisms to other tsefalosporinam, penicillins, and other aminoglikozidam antibiotic), the good portability.

     Enter ceftriaxone for adults and children over 12 years of age in the dose 1 g 1 - 2 times a day. In severe cases, the daily dose increased to 4 grams (two with a 12 hour interval).

     Children younger set 20-80 mg / kg once a day, premature children in a daily dose of not more than 50 mg / kg.

     In severe kidney and liver insufficiency dose should be reduced.

     Patients gonorrhoea is a single .25 g intramuscularly. In other infections, length of treatment depends on the severity of disease. Recommended introduce product (as chemotherapy and other means) not less than 3 days after the normalization of body temperature.

     Possible side effects and contraindications basically the same as when applying tsefotaksima.

     Form release: in vials of 0.25 and 1 year to kind of attached to vnutrimyshechnogo ampoule with the solvent (2 or 3, 5 mL), containing lots (to reduce pain).

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