Chloral hydrate (chlorali hydras)
HLORALGIDRAT (Chlorali hydras). 2, 2, 2-Trihloretandiol-1, 1
Synonyms: Aquachloral, Chloradorm, Chloraldurat, Chloral hydrate, Chloratol, Dormel, Dormiben, Hydral, Lorinal, Lycoral, Medianox, Noctec, Nycoton, Somnos, Sorosil and others.
Colorless transparent crystals or powder with a characteristic melkokristallichesky eapahom sharp and slightly bitter taste unique. Very easily soluble in water and alcohol. At Air slow surface. Gigroskopichen.
Soothing, sleeping and analgezic means; In high doses, close to the toxic, has narcotic properties. Provides complex effect on the nervous; In small doses is weakening brake processes in large-down processes voebuzhdeniya; Toxic doses severely repressed anxiety nerve cells.
Now rarely used as a soothing (adult-to 0.2 - 0.5 grams per reception) or pain (on 0.5-1 g) means. Children, depending on age and the testimony appoint 0,05 - 0,75 g per reception. Accepted inside or give enemas in diluted form, coating materials (due to irritant in the mucosal lining of the stomach and bowel). The product is rapidly absorbed. Sleep comes in 15 - 20 minutes, continues 6 to 8 h; Often accompanied by a decrease AD; Possible vomiting.
Most hydrate is used in the mental institution and as a means to protivosudorozhnoe spazmofilii, tetanus, etc.
The children also apply to the intensive care convulsant status. Children under age 5 appoint enema in 15 2% 20 ml solution, older children - 40-60 ml of 3% solution. If necessary, enter through 1 - 2 half-hour dose. At the same time, designate Phenobarbital and difenin.
Higher doses for adults inside and enema; Off 2 g daily 6 d.
Contraindications to heavy cardiovascular diseases, liver and kidney.
In a lengthy application may addictive.
Form release: powder.
Included in dental droplets <Dent>.
Storage: List B. The well ukuporennoy packaging keeps out of light in a cool place.
Rp. : Chlorali hydratis 1.0
Mucilaginis Amyli
Aq. destill. aa 25 ml
M.D.S. At one enema (adults)
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Materials allowed to copy only with the active hyperlink to the handbook of medicines
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