Chlorprothixene (chlorprothixenum)
HLORPROTIKSEN (Chlorprothixenum).
502 Hlor-9- (3-dimetilaminopropiliden) - tioksantena hydrochloride.
Synonyms: Chlorprothixeni hydrochloridum, Chlorprothixene hydrochloride, Chlothixen, Minithixen, Tactaran, Taractan, Tarasan, Trictal, Truxal, Truxil, Vetacalm and others.
On chemical structure similar to aminazinu; Difference is that instead of nitrogen atom in the central part tritsiklicheskogo kernel contains carbon connected dual connection with side chain.
The product has a sedative effect and antipsihoticheskoe increased psychological effect and analgeticheskih funds. It has expressed protivorvotnoy activity. Provides adrenoliticheskoe moderate, weak and relatively strong protivosudorozhnoe antiholinergicheskoe effect. There has katalepticheskogo action.
Adjunct combined effect of hlorprotiksena moderate antidepressant effect.
Apply with psychosis and psihonevroticheskih state, accompanied by anxiety, fear, psychomotor stimulation, aggressiveness, including paranoid disorders, schizophrenia circular, with a simple low psihopatopodobnoy with schizophrenia and nevrozopodobnoy STDs and other mental illnesses. The product is effective in treating acute alcoholic Psychosis. In small doses can be used as a means of calming neuroses, altered sleep (alone and in combination with diet), skin itching and others.
Apply as protivorvotnoe funds.
Assign inside (to food), or intramuscularly.
When treating the mentally ill adults Chlorprothixene appointed interior, from 0,025 - 0,05 g (25-50 mg) a day (3 - 4 admission), followed by increasing doses of 25 to 50 mg total daily dose 0.2 - 0.4 g (200-400 mg). In resistant cases increased dose to 0.6 - 0.8 was reached therapeutic effect gradually reduce the dose.
Intramuscularly (deep in the upper outer Quadrant buttocks) product to enter patient with acute mental institution (including acute alcoholic psychosis with the expressed psychomotor stimulation, accompanied by fear and anxiety), and in other states when needed for rapid intervention, or if the patient is unable to take drugs inside (severe vomiting, etc.). Once the state allows, moving to pick up the drug in tablet form.
Intramuscularly imposed on 25-50 mg 2 to 3 times a day (as protivorvotnoe 12, 5-25 mg). In severe cases, an increased dose to 100 mg.
In neuroses appointed interior of 5 - 10 - 15 mg 3 or 4 times a day.
Chlorprothixene generally well tolerated by, it is exhaustion, despondency. In some cases, there is confusion, tachycardia, hypotension, drought in the mouth. Extrapyramidal disorders occur rarely. Possible temporary neutropenia, a violation of liver function, increase skin sensitivity to sunlight.
The product contraindications to alcohol poisoning and inaccurate, and the propensity to collapse, with epilepsy, parkinsonizme, violations of blood, liver defeat.
It designate product, and other adjunct and tranquilizers, while the transport drivers and those of other professions that require rapid mental and physical reactions.
Method of production: tablets (Bean) to 0,015 and 0.05 g (15 and 50 mg) in the package of 50 cards; 2, 5% solution in the ampoule and 1 ml (25 mg).
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Materials allowed to copy only with the active hyperlink to the handbook of medicines
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