Chondroitin sulfate (Chondroitin sulfate)

     Chemical name: Hondroitin-4- (gidrogensulfat) (in the form of sodium salt)

     Description: Vysokomolekulyarny mukopolisaharid. White or nearly white with a yellowish tinge powder or dried white amorphous powder odourless. Gigroskopichen.

     Pharmacology: Farmakologicheskoe action-hondroprotektivnoe, hondrostimuliruyuschee, minutes.

Participates in the building of basic substances bone and cartilage. Calcium Improves thousand cuts in exchange tissue inhibited enzymes that violate the structure and function of joint cartilage, slowing degeneration of cartilage tissue. It stimulates the synthesis glyukozaminoglikanov, normalize metabolism gialinovoy tissue to regenerate cartilage surface and surface bags. Warns compression connective tissue, increases vnutrisustavnoy liquid products, increases mobility affected joints. Slow bone resorption reduces calcium loss accelerates bone reparation processes, slowing the progression osteroarthrose. Has analgeziruyuschim action reduces the pain of making joints, pain in peace and in walking, expressivity inflammation, helps reduce the need for NPVS.

After receiving oral rapidly absorbed from the digestive. Cmax achieved through 3-4 hours Sinovialnoy fluid accumulates in the joints. Bioavailability is 13%. Report the kidneys.

     Application: Degenerativno- Dystrophic diseases of joints and spine: primary arthrosis, mezhpozvonkovy ups, Osteoarthritis, osteoporosis, Parodontologija, bone fractures (to accelerate bone education feet).

     Contraindications: Hypersensitivity, prone to bleeding, trombophlebitis.

     Restrictions on the use: Pregnancy, breast feeding, child age.

     Application of pregnancy and breast feeding: When pregnancy and breast feeding may only after consulting a doctor.

     Adverse actions: allergic reactions (skin itching, erythema, Urticaria, dermatitis), hemorrhage at the injection site; Rarely, nausea, vomiting.

     Dosing and Administration: inside, vine small amount of water. Adults at 750 mg two times a day during the first three weeks, followed by 500 mg 2 times a day. Children under 1 year of 250 mg / day, from 1 to 5 years, 500 mg / day, over 5 years - 500-750 mg per day.

V / m (tentatively rastvoriv liofilizat in 1 ml of water for injection) for 100 mg a day, with an injection of the fourth dose increased to 200 mg. Course 25-35-injection re-through 6 mo.

External, causing the skin above the fireplace defeat 2-3 times a day and the entire 2-3 minutes to complete saturation. The course of treatment is a 2-3 week. If necessary, repeat the course.

     Precautions: If allergic reaction or haemorrhage treatment should stop. Avoid getting drugs to skin infections and open wounds.

Materials allowed to copy only with the active hyperlink to the handbook of medicines