TSITALOPRAM (Citalopram).

     1-[3-(Dimetilamino) propyl] -1 - (p-ftorfenil) -5 - ftalankarbonitril.

     Synonyms: Tsipramil, Cipral, Cipramil, Lupram, Sepram.

     Refers to "balanced" drugs dominated anksioliticheskogo action.

     Along with the electoral inhibition neyronalnogo taking serotonin, blocking gistaminovye, holino- and M-Adrenergic.

     When you receive inside bioavailability of 80%, S-max 2-4 h, T 1 / 2 to 36 h; Biotransformation exposed in the liver, slowing activity tsitohroma R 450; Return with urine and faeces.

     Apply different etiology of depression and structure.

     Assign inside adult 0,02-0,06 g (20-60 mg) one time a day older 0,02-0,04 g (20-40 mg) per day. Antidepressant effect develops slowly (by 2-4 weeks).

     Possible side effects: headaches, urination disorders, tremor, spasmodic reaction, tachycardia, hypotension ortostaticheskaya, migraine, allergic reactions, etc.

     The product contraindications in pregnancy and breast feeding.

     In connection with the ability to reduce the concentration of attention and speed of reaction, should be applied with caution to those administering vehicles and working with dangerous machinery.

     Increases effects sumatriptana and other serotoninergicheskih and MAO inhibitors (hypertension can Stroke).

     Form release: pills to 0.02 and 0.04 g (20 and 40 mg) (N. 14, 28).

     Storage: List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines