KLOMETIAZOL (Clometiazole).

     Is etandisulfonatom hlormetiazola, ie 5 - (2-chloroethyl) -4 - metiltiazola etandisulfonat.

     Synonyms : Geminevrin, Heminevrin, Gemineyrin, Chlomethiazole, Chlormethiazole, Clometiazole, Clomiazine, Distraneurin, Distrapax, Hemineurine, Hemineurin, Heminevrin, Somneurin, Somnevrin.

     On chemical structure can be seen as part of a molecule of thiamine (vitamin B1), but not vitamin properties, and has a sedative, sleeping pills and protivosudorozhnoe effect.

     Applied with sleep disorders, epilepsy status, eclampsia and predeklampsicheskih state in a position to proceed with an acute, as well as for pain birth. Is effective in the treatment of opioid syndrome in alcoholism.

     Assign inside and intravenously. When administered in the form of capsules and is absorbed more quickly than in the employment in pill form.

     As relief funds are designated for 2 - 4 capsules (or pills) at night (or in two installments), as a sedative-1 - 2 capsules (pill) per day (before meals).

     When epileptic status and delirii injected 40-100 ml of 0.8% solution for 3 to 5 minutes or drip for 60-150 drops per minute on the offensive sleep, then Infusion slow, maintaining a superficial sleep. Total for 6 to 12 hours to enter 500-1000 ml. You can then receive the drug inside.

     In severe cramping syndrome appointed to 2 - 4 capsule, and if necessary through an additional 2 capsules before the rest and sleep.

     Applied also to alleviate cramping syndrome to 3 capsules a day for two days, then on two capsules a day is three days and one capsule a day for 4 days. The course is normally continues 9 days.

     For anesthesia delivery are 2-3 capsules, if necessary, an additional 2 to 3 capsules after 3 h (total no more than 7 capsules).

     In eclampsia injected 30-50 ml of 0.8% solution for 60 drops per minute, after wasting dose reduced by 15 to 10 drops per minute.

     In severe Manic institute imposed 40-80 ml of 0.8% solution.

     Intravenous introduction gemineyrina can cause local flebit. The drug intravenously injecting slowly. It should take into account the possibility depressed respiration, development hypotension and collapse. When ingestion possible diarrhoeal phenomenon.

     For alcoholism gemineyrin phenomenon can cause psychological dependence. Therefore, drug use is not more than 6 - 7 days, appointed him in the minimum dose providing therapeutic effect.

     Method of issuance : capsules containing 192 mg of hlormetiazola founding in peanut oil, or 500 mg gemineyrina; Tablets 500 mg gemineyrina; 0.8% solution in bottles of 100 ml of 500 metres.

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