KRESTOR (Crestor)

     Synonym : Rozuvastatin, Rosuvastatin.

     The composition and the form of :

Pill-coated (Table 1).

- rozuvastatin (in the form of calcium rozuvastatina) 10 mg, 20 mg, 40 mg.

Support substances : lactose Monohydrate; AICC; calcium phosphate; krospovidon; magnesium stearate; polymer; glycerin suggesting; titanium dioxide (E171); red iron oxide (E172); Purified water

in e blisters 7 pc. in the stack cartons 1 blisters; or e blisters 14 pc. in the stack cartons 2 roubles (10 mg and 20 mg);

in e blisters 7 pc. in the stack cartons 1 or 4 roubles (40 mg).

     Dosing and Administration : inside, is not liquid, squeezed water at any time of day, regardless of meals. Treatment Krestorom always to start with a dose of 10 mg in patients previously receiving statins, and the translation from other drugs in this group. Most patients therapeutic effect is achieved with 10 mg rozuvastatina admission. If necessary dose can be increased to 20 mg four weeks. Increasing doses up to 40 mg may be carried out only in patients with severe NCEP with a high risk of cardiovascular complications (especially in patients with a family NCEP), which did not achieve the desired result in the admission therapy dose 20 mg, which will be under the supervision of a physician.

No dose adjustment in older patients, in patients with renal insufficiency light or medium gravity. Application Krestora contraindicated in patients with renal failure expressed, as well as liver diseases in the active form. Experience with the drug in patients with a score above 9 on a scale Chayld- Pugh missing. Not recommended Krestor children (the efficacy and safety of the children has not been established). Experience of application in paediatric practice limited to a small number of children (8 years and older) with homozygous family NCEP.

     Shelf life : 3 years

     Storage conditions : List B. When temperature is not above 30 ° C

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