DAMILENA MALEINAT (Damileni maleina s). 5 - (3-Dimetilaminopropiliden) -10,11 - digidrodibenzotsiklogeptena maleinat.

     Synonym : Amitriptylini maleas.

     White or yellow crystalline powder. Little is soluble in water, soluble in alcohol.

     The structure of the early preparation is different from amitriptyline, but unlike it is not hydrochloride, a maleinatom.

     On pharmacological properties and therapeutic action has no advantages over amitriptyline.

     In connection with the greater relative molecular mass (393, 5) than any amitriptyline hydrochloride (314) damilena maleinat be appointing several high doses.

     Usually, the initial dose of the drug inside the 0,025 g three times a day, then gradually increase the dose to 0.15 - 0.3 g / day (sometimes up to 0.4 g) to achieve therapeutic effect in a subsequent dose gradually.

     Possible complications and contraindications are the same as in the application of amitriptyline.

     Product : gelatine capsules of 0.05 g (50 mg).

     Storage : List B. In dry, the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines