Deprenil (deprenyl)

	Deprenil (deprenyl) DEPRENIL (Deprenyl). L - (-), N - (1-fenilizopropil) -N- metil-N-2- propinilamin. Synonyms : Selegilin, Yumeks, Selegiline, Eldepryl, Jumex, Tumex. By chemically similar to ephedrine (see) and other simpatomimeticheskim amines, but action was unusual in that a specific inhibitor monoaminoksidazy (MAO) type B. The other MAO inhibitors, unlike deprenila operate MAO-type or have a mixed impact (on MAO A and type B). Application deprenila as antiparkinsonicheskogo funds based on the fact that the brain predominantly MAO B type and inhibition of this enzyme results in a higher concentration in the tissues of the brain mediator monoaminov, including the contents of striped body start. Especially expressed increase in the release of neuronal ekstrapiramidnoy system while applying deprenila with L-Dov (levodopa). Deprenil reduces the effect of levodopa and lengthens it. Therefore deprenil in parkinsonizme used in combination with levodopa. There is evidence that the application deprenila with antiparkinsonicheskimi drugs in patients parkinsonizmom improved lipid exchange rates. Assign deprenil on 0,005 - 0,01 g (1 - 2 tablets) a day (on one tablet morning and evening or morning). Dose choose individually. When the dose effect is not increased. A few weeks from the start of treatment can be limited to lower doses deprenila, however, when prolonged treatment deprenila performance can be affected. �� . Deprenil could be combined with madoparom or nakomom. Side effects in treating deprenilom combined with levodopa or products containing it are similar to trends in the application of a drug levodopa, but they can grow. There should be appointed deprenil in extrapiramidale diseases not related to the lack of something (in essentsialnom tremor, trochaic Gentingtona etc.). Form vmpuska : pills to 0,005 grams (5 mg) and 0.01 g (10 mg) in a package of 10 pieces. Produced in Hungary.
Materials allowed to copy only with the active hyperlink to the handbook of medicines