DEZAMINOOKSITOTSIN (Desaminooxytocinum).

     Synonyms : Sandopart, Demoxytocin, Demoxytocinum, Sandopart.

     The synthetic polypeptide that is different from the oxytocin that cysteic in regulation dezaminirovan 1.

     The white amorphous powder. It is soluble in water and alcohol.

     According to the dezaminooksitotsin close to oxytocin, but resistant to enzymes destroying oxytocin. The drug is well absorbed through the mucous membrane of the mouth, not saliva enzyme degrades, so can be used transbukkalno.

     The specific activity dezaminooksitotsina (like oxytocin) is expressed in units of (ED or IU) and defined by biological, reduction of isolated rat uterine horns.

     Vazopressornogo of preparation does not provide, allowing for its patients suffering from hypertension.

     Applied to initiate and enhance labor activity, accelerating involution of the uterus in the postpartum period and stimulate lactation.

     Is in the form of tablets. Each tablet contains 50 ED drug. A pill for cheek alternately with the left and right hand and keep the mouth (not liquid and not proglatyvaya) to complete resorption (about 30 minutes).

     For rodovozbuzhdeniya and stimulation delivery designate pills again 30 minutes from the interval. The number of tablets varies, depending on the particular case. Normally, the maximum dose for initiating and facilitating delivery of 500 ED (10 tablets), in rare cases, ED-900. When regular, strong labor following single dose dezaminooksitotsina reduced by half (1 / 2 tablets), or increase the interval between the introduction (1 hour). In the absence of effective drugs can be taken again after 24 h.

     At the time of dezaminooksitotsina there should be other oksitotsicheskie substance.

     To stimulate lactation appointed by the 2 nd to 6 th day of the postpartum period to 25 ED-50 (1 / 2 - 1 tablet) for 5 minutes and breastfeeding 2 to 4 times daily.

     Indications are the same as for oxytocin.

     Product : pills containing 50 ED, orange glass in banks to 10 pieces.

     Storage : List B. In dry, the dark place at a temperature no higher than + 25 C.

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