DIGIDROERGOTAMIN (Dihydroergotaminum).

     Available in a metansulfonata (mezilata).

     Synonyms : Ditamin, Klavigrenin, Agit, Angionorm, Clavigrenin, Cornhidral; DH-Ergotamin, Diergotan, Dihydergot, Dihydroergotamine mesilate, Dihytamin, Ditamin, Ergomimet, Ergovasan, Ikaran, Migretil, Migrifen, Tonopress, Vasogin, Verteblan and others.

     The main pharmacological properties is a drug-adrenoblokiruyuschaya activity which has a 1-and a 2-adrenoretseptory.

     Applied mainly migraines, and diseases Reynaud and other violations of peripheral blood circulation.

     Available for admission into a solution containing 1 ml of 0,002 grams (2 mg) digidroergotamina metansulfonata and in the form of tablets containing 0.0025 g (2, 5 mg) drug, and the injection of 1 mg ml , containing 0,001 grams (1 mg) drug.

     Is usually on the inside of 10-20 drops (1 / 2 cup of water) 1 3 times a day. In severe forms of migraine enter immediately after the first signs of 1 ml intramuscularly, and if necessary, give the same dose again. To prevent migraine headache and vascular genesis take morning and evening for one tablet (2.5 mg) or 20 drops of 0.2% solution (2 mg) 2 - 3 times a day. Optimal dose picked individually.

     For admission into possible drug nausea, vomiting, weakness, drowsiness, in rare cases, parestezii, diarrhea. When parenteral and a sensitivity that can be kollaptoidnoy reaction. Following intramuscular injection patient should be some time in the prone position.

     The drug is not suitable for hypotension, expressed atherosclerosis, organic defeat heart, strokes, in violation of the liver and kidney at the oldest ages, as well as pregnancy and breast-feeding the child.

     Method of production : 0.2% solution (2 mg in 1 ml = 20 drops); 0.1% solution (1 mg) in 1 ml ampoules; Pills to 0.0025 g (2, 5 mg).

     Storage : List B. In the dark place at a temperature of not more than + 25 'C.

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