DILTIAZEM (Diltiazem) *.

     D Atsetoksi Z-2, 3-digidro-5- [2 - (dimethylamino) ethyl] -2 (2-methoxyphenyl) -1, 5-benzotiazepin-4 (5 H), it hydrochloride.

     Synonyms : Diakordin, Dilzem, Cardiel, Acalix, Aldiazem, Altiazem, Alzidem, Anginyl, Angizem, Cardil, Cardizem, Diacordin, Diladel, Dilatam, Diltiazem hydrochloridum, Dilticard, Dilzem, Incoril, Litizem, Tilazem, Viacor, Zildem and others.

     Antagonist calcium ions to be applied in strokes (including strokes Printsmetala) and hypertension. Has hronotropnoe negative effect and reduces the frequency of heart. It may slow atrioventrikulyarnuyu conductivity and lower anxiety atrioventrikulyarnogo hub. Reduces vascular tone and total peripheral resistance in hypertensive disease. Antianginalnoe effect due to a decrease in attacks prednagruzki, dilatation of the coronary vessels and improving the supply of oxygen heart. It has also antiaritmicheskoy activity.

     As of diltiazem close to verapamil, but somewhat stronger effect on the vascular smooth muscle and a wire system of the heart. Relatively less nifedipinom expressed with peripheral vazodilatatornoe effect and the reflected tachycardia.

     When applied in various forms IBS and hypertension.

     Assign diltiazem inside. Dose choose individually from 0.03 g (30 mg), 3 to 4 times a day to 0,18 - 0,3 g (Z00-180 mg) a day.

     The drug is usually well but need to monitor performance and portability. With insufficient effects add other drugs.

     Method of production : tablets of 0.03 and 0.06 g (30 and 60 mg); Pill-acting (coated) of 0.09 or 0.12 grams (90 or 120 mg). Assign to one pill (sometimes for 2 pills) 1 -2 times a day.

Materials allowed to copy only with the active hyperlink to the handbook of medicines