DIOKSONY (Dioxonium). 1, 2 - Bis (4-pirrolidinometil-1 ', 3'- DIOXOLANYL-2) - ethane diyodmetilat.

     Melkokristallichesky yellow powder. Very easily soluble in water, it is difficult to alcohol. Aqueous solutions with sterilization is not changing.

     Is miorelaksantom mixed action. First is depolarization phase, and then acts as antidepolyarizuyuschy muscle.

     In the second phase Neostigmine relaxed dioksoniya.

     When ether anaesthesia and ftorotanom act dioksoniya increase.

     Applied to relax muscles and stops breathing spontaneously, both pre - and post-introduction ditilina.

     Enter intravenously. After a preliminary introduction ditilina apply dioksony dose of 0.03 - 0.04 mg / kg, and in the application of self-imposed dioksony heavy dose of 0.04-0.05 mg / kg. Muscle relaxation nastupet through 1 5 3 minutes and lasts usually 20 to 40 minutes. If necessary lengthening effect impose an additional 1 / 2 to 1 / 3 of the initial dose.

     Signs kurarizatsii can be resolved (by the end of the operation) prozerinom (2 to 4 mg), after the introduction of atropine.

     Dioksony applied only if conditions for holding tank.

     The drug should be used with caution in infants. In some cases, medication may cause prolonged muscle relaxation.

     Widespread use dioksony no.

     Product : 0.1% solution in ampoules to 5 ml (5 mg in the ampoule).

     Storage : List A. In the dark spot.

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