DIETILSTILBESTROL (Disethylstilboestrolum). trans-3, 4-Di (steam-oksifenil) - geksen-3.

     Synonyms : Agostilben, Diethylstilbestrol, Diethylstilbestrolum, Estrobeme, Estromenin, Neoestranol, Newoestranol, Oestramon, Oestrogenin, Oestromenin, Oestrosyntal, Oroestron, Pabestrol, Sibarol, Stilbestrol, Stilbetin, Stilboestroform, Stilboestron, Stilbofolin, Stilboral, Synestrin, Synthoestrin, Syntofollin and others.

     The white crystalline powder. Mg of alcohol, ether, fatty oils; Very little is soluble in water.

     Synthetic compounds, have oestrogenic effects. At the level of activity than Estrone and sinestrol. At 1 mg contains 20000 ED.

     Earlier dietilstilbestrol relatively widely used as a means of oestrogenic in gynecologic practice, and the isolationist and prostate gland cancer. Currently, in connection with the side effects it has limited application.

     Sometimes dietilstilbestrolom use in the treatment of breast cancer in women. Like sinestrol, he was appointed only to women over 60. Dose dietilstilbestrola in connection with its greater activity should be 2 to 3 times less than the dose sinestrola.

     Higher-time and daily reports on the convocation intramuscularly with malignant tumors 0.06 g.

     Contraindications to the use of the same as for estrona. It should appoint a drug in liver and kidney diseases.

     Treatment must be carried out under the close supervision of a doctor.

     Product : 3% solution in oil in capsules and 1 ml (30 mg in 1 ampoule); Use only in the treatment of patients with malignant neoplasms.

     Storage : List B. In the dark spot.

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