EPOETIN ALFA (Epoetin alfa).

     Synonyms: Epreks, Eritrostim injection, Eprex, Erythrostimum pro injection.

     Glikoproteid containing 165 amino acid residues.

     Mitosis and stimulating cells differentiate eritroidnyh predecessors, increases the number of blood and increases hemoglobin.

     In a subcutaneous bioavailability of 25%, S-max 12-18 x T? up to 24 h (with intravenous introduction, 5-6 h).

     Apply with anemia different origins (with chronic renal failure, hemodialysis, in the face of HIV treatment zidovudine, tsitostatikami; For premature babies, etc.).

     Assign subcutaneously or intravenously (struyno) first usually 50-75 ED / kg (up to 200 ED / kg) three times a week, supporting dose 30 ED / kg 3 times weekly.

     Possible side effects: increased blood pressure, convulsions, trombotsitoz, thrombocytopenia, tromboembolicheskie complications giperkaliemiya, blindness condition, allergic reactions, etc.

     The product contraindications with resistant hypertension, pregnancy and breast feeding.

     Form release: injection in the ampoule and 1 ml (500, 2000, 4000 and 10000 IU), in vials of 0.5 ml (ED 1000), and 1 ml (2000, 4000 and 10000 ED) and syringes to 0 , 3 ml (ED 3000), 0.4 mL (4000 ED), 0.5 mL (1000 and 2000 ED), and 1 ml (ED 10000).

Materials allowed to copy only with the active hyperlink to the handbook of medicines