ERINIT (Erynitum).

     Pentaerythritol tetranitrate (PETN).

     C inonimy: Nitropenton, Angicap, Dilcoran, Neo-Corovas, Nitrinal, Nitropentaerythrit, Nitropenthrite, Nitropenton, Pentaerithrityli tetranitras, Pentaerithrityl tetranitrate, Pentaerythrit tetranitrate, Pentafin, Pentalong, Pentanitrine, Pentanitrol, Pentaryl, Pentaryt, Pentitrate, Pentral, Pentrit, Pentritol, Pentrittae , Perangil, Peritrat, Quintrate, Vasocor, Vasodilatol and others.

     The white crystalline powder. Nerastvorim in water, soluble in alcohol. Explosive.

     On chemical structure and pharmacological properties similar to nitroglycerin, but compared with the slowly absorbed light skin and has a slower, less dramatic but more prolonged effect. Effect of admission is 30 inside 45 minutes, with sublingvalnom application-after 15 - 20 minutes. The duration of effect 4 - 5 hours Hypotensive effect expressed less than nitroglycerin.

     Apply with chronic coronary insufficiency. The product warns offensive attacks stenocardia or reduce their number and facilitates over. For kupirovaniya attacks Ernits maloprigoden at the slow onset of effect.

     Accepted inside (for 1 hour before eating) in the form of tablets of 0,01 - 0,02 g (10-20 mg, or 1 - 2 pills) through 4 to 6 hours To prevent attacks stenocardia night sometimes appoint 0.02 grams of sleep. The course of treatment usually 2 to 4 weeks. Repeated courses assign intermittently, the length of which depends on the period of the disease. For too long the drug may receive continuous development of tolerance.

     In modern data Ernits less efficient than other organic nitrates. Nitrosorbid, in particular, is more pronounced and 2 times more effective than Ernits.

     Ernits generally well tolerated by. Adverse events observed in the employment of nitroglycerin (headache, noise in the ears, dizziness), the application of rare and less erinita expressed; Sometimes there is discomfort bowel function (diarrhoea). As the dose, or after receiving the drug side effects are.

     In connection with a relatively good portability Ernits can be used in the absence of other similar products, with a selection of doses.

     Contraindications are the same as for other organic nitrates.

     Form release: pills to 0.01 and 0.02 g (10 and 20 mg).

     Storage: List B. In a cool, sheltered from the light away from the fire.

     Under the title "Dilcoran 80" pills are produced abroad erinita prolonged action, containing 0.08 g (80 mg) drugs. Such tablets are still about 12 hours

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