Carvedilol (esmolol)


ESMOLOL (Esmolol).
     (+) -4-[2-Oksi-3- [(1-methylethyl) amino] propoksi] fenilpropionovoy acid methyl ester.
     Synonym: Breviblok, Brevibloc.
     Kardioselektivny V1- short of beta (T 1 / 2 of 9 min). Partial agonisticheskoy and membranostabiliziruyuschey activity is not.
     Apply mainly for short-term treatment supraventrikulyarnyh aritmy (flickering and trepetanie predserdy, sinusnaya tachycardia), and hypertension during and after operations. Used also tireotoksicheskom Stroke, acute myocardial heart attack, unstable feohromotsitome stenocardia.
     Enter intravenously kapelno a 1% solution (20 ml 25% concentrate in 500 ml solvent) at speeds 0,05-0,2 mg / kg per minute; In acute myocardial heart attack - 0.5 mg for 1 min, if necessary this repeat dose in 2 minutes, and then at a speed of 0,05-0,3 mg / kg per minute).
     Possible side effects, contraindications and limitations to the use of the same as other Finally adrenoblokatorov (see Anaprilin and Atenolol).
     Method of issuance: 1% injection in vials of 10 ml and 25% concentrate for intravenous fluids in the ampoule to 10 ml.
     Storage: List B.

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