ESTAZOLAM (Estazolam).

     8 Chloro-phenyl-4 N-s- triazolo [4,3-a] [1,4] - benzodiazepine.

     Synonym: Nuktanol, Nuktanol.

     The chemically different from nitrazepama and flunitrazepama that contains molecules "embedded" triazolnoe ring and chlorine atom (instead of NO2) in fenilnom kernel. However, it is very close in structure to triazolamu.

     Has anksioliticheskoy, Bio, widespread and relatively weak miorelaksantnoy and protivosudorozhnoy activity.

     Quickly and completely absorbed in the digestive, T 1 / 2 is about 17 h; Metabolized in the liver, kidneys displayed.

     Apply with neuroses with anxiety disorders syndrome, heightened anxiety and sleep disorders, as well as epilepsy (support funds).

     Assign disorders in a position to 0,004-0,006 grams (4-6 mg) per day (reception 2-3), a pill for half an hour before sleep at 0,002-0,004 grams (2-4 mg) ; older patients - 0,001 (1 mg). Tablets proglatyvayut is not razzhevyvaya, ?high small amount of water.

     Among the side effects noted daily headaches and ataxia.

     Increases of drugs ugnetayuschih TSNS.

     Form release: pills to 0,002 grams (2 mg) (N 20).

Materials allowed to copy only with the active hyperlink to the handbook of medicines