ETAMZILAT (Etamsylatum). 2, 5-Dioksibenzolsulfonata dietilammonievaya salt.

     Synonyms: Ditsinon, Aglumin, Altodor, Cyclonamine, Dicynen, Dicynene, Eselin, Etamsylate, Ethamsylate, Impedil and others.

     White with a rosy tinge crystalline powder. Easy soluble in water, soluble in alcohol.

     The product improves education in capillary walls mucopolysaccharides high molecular mass and enhances stability capillary permeability to normalize their pathological processes, improves microcirculation; Also gemostaticheskoe effect. Hemostatic effects associated seem to trigger action on the formation tromboplastina. The product promotes education III factor collapse blood normalize adhesion of platelets. The product has no effect on prothrombin time, no giperkoagulyatsionnymi properties and is not conducive to education embolism.

     Apply etamzilat to prevent and stop bleeding in the capillary diabetes angiopatiyah, rapid intervention in otorinolaringologicheskoy (tonsillectomy microsurgeries operations left, etc.), eye (keratoplasty, remove cataracts, protivoglaukomatoznye operations and other sensitive operational interference), dental (cyst removal, granules, dental extractions, etc.), urologic (after prostatektomii etc.), in surgery and gynaecology (especially in the operations of highly vaskulyarizovannyh tissue) practice, as well as in cases of emergency when disease and lung krovotecheniyah and haemorrhagic diathesis.

     Assign intravenously, intramuscularly, podkonyunktivalno, retrobulbarno and inside.

     Gemostaticheskoe of etamzilata developed through the introduction of intravenous 5-15 minutes maximum effect comes through 1 - 2 h, the effect lasts 4 to 6 hours or more. With the introduction vnutrimyshechnom effect is somewhat slower. When you receive inside a maximum effect through 3 hours.

     In preparation for introducing preventive intravenously or intramuscularly for 1 h before the operation dose of 2 to 4 ml (1 - 2 ampoule), which corresponds to 0.25 - 0.5 g etamzilata, or giving into 2 - 3 tablets (to 0.25 g) for 3 h prior to the operation. If necessary, enter 2 - 4 ml intravenously during the operation. At risk of postoperative bleeding introduce preventive 4 to 6 ml (2 - 4 ampoule) per day or are from 6 to 8 tablets per day (evenly throughout the day).

     In therapeutic purposes (in uterus) are introducing veins or intramuscularly once 2 to 4 ml, and then every 4 to 6 h and 2 ml or give 2 tablets.

     You can enter kapelno vein, adding to the usual solutions for Infusion. Not to be confused etamzilat in the same syringe with other drugs.

     When treating Metro and menorragy appoint etamzilat to 0.5 grams inside or 0.25 g parenteral transmission, every 6 h for 5 - 10 days later-at 0.25 g inside four times a day, or 0 25 g parenteral transmission two times a day during hemorrhage, and the last two cycles.

     When treating haemorrhagic diatezov and diseases of the blood product designate courses on 1, 5 g per day through intervals inside of the 5-14 days. In severe cases are treated with parenteral introduction of 0.25 - 0.5 g 1 - 2 times a day in a Z-8 days, and then designate the interior.

     In diabetic mikroangiopatiyah (retinopathy of haemorrhage) designate etamzilat courses for 2 - 3 months, giving 1 - 2 pills three times a day or imposing intramuscularly 1 ampoule (2 ml), 2 times a day for 10 to 14 days.

     Podkonyunktivalno and retrobulbarno impose 1 ml.

     It should not be used in etamzilat haemorrhage caused by anticoagulants. Caution is necessary in patients with brain or deep in history.

     Method of issuance: 12, 5% solution in ampoule of 2 ml (250 mg) in the package of 10 or 50 vials; Tablets of 0.25 grams banks lighting glass of 50 or 100 pieces.

     Storage: List B. In sheltered from the world scene.

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