Fenoterol (fenoterolum)
FENOTEROL (Fenoterolum) *. 1-(3, 5-Dioksifenil) -2 - (para-acid a-methyl fenetilamino) - ethanol.
Issued in the form hydrobromide.
Synonyms: Berotek, Partusisten, Airum, Berotec, Dosberotec, Partusisten, Segamol and others.
According to the structure and actions similar to ortsiprenalinu, but is more selective blokatorom b 2-adrenoretseptorov and has therefore more selective, strong, relatively long operation in bronhospasticheskih condition with less side events (tachycardia and other violations of the cardiovascular system). There are indications that the drug has bronholiticheskoe operation and simultaneously enhances functionality mertsatelnogo epithelium and accelerates mukotsiliarny transportation.
Under the title "Berotek (Germany) product is used for the treatment and prevention of bronchial asthma, chronic bronchitis and astmaticheskogo and other bronchopulmonary diseases involving bronhiolospazmom.
Form release: in aerosol containers plus metering valve nozzle with a click of 0.2 mg drug. Manufacturing one breath 2 to 3 times a day. If, after the first inhalation effects not come, after 5 min repeat inhalation. Following inhalation producing intervals with 5 hours
The use of the drug can be combined with mucolithic (see Bromgeksin, Lazolvan) derivatives ksantina (see Theophylline) Kromolina- sodium (see) stimulation. Bronhorasshiryayuschee effect while increasing.
Special medicinal form fenoterola (Beroteka) plus holinolitikom ipratropium- bromide (atroventom) published in Germany under the title "Berodual (see), a product containing fenoterol combined with kromolin- sodium, issued under the title" Ditek "(see . Kromolinnatry).
Possible side effects when applying fenoterola: finger tremor, anxiety, heart; Sometimes a sense of fatigue, dizziness, headache, sweatiness. In these cases, reduce the dose.
Contraindications-see Izadrin.
Form release: in aerosol containers to 15 mL plus metering valve, containing 300 single dose (1 mg dose contains 0.2 fenoterola hydrobromide).
Storage: at a temperature of not more than 25 'C away from fire and heat sources.
In connection with the relaxing effects on the uterine musculature caused by stimulation b 2-adrenoretseptorov, fenoterol found special applications as tokoliticheskogo and available for use in obstetric practice called "Partusisten" (see Resources affecting the uterine musculature).
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