Fibrin (fibrinogenum)
FIBRINOGEN (Fibrinogenum).
It is a natural component of blood. Moving fibrinogena in fibrin unfolding under the influence of thrombin, provides the ultimate stage of collapse blood-education bunch.
Fibrin used as haemostases funds from the plasma of blood donors.
Dry porous mass kremovatogo white or color. The product should be dissolved for not more than 10 minutes in the specified on the label of water, heated to 25 or + + 35 'S; PH received solution 6, 5-7, 4. Solution opalestsiruet (V solution may contain a small amount of flake; After filtering through a uniform system for blood transfusions he dolzhensoderzhat flakes and other mechanical impurities.) .
Fibrin apply when sensing and afibrinogenemii, krovotecheniyah in trauma, surgical, oncological practice massive krovotecheniyah in obstetric and gynaecological practice (premature abruptio placenta, birth amidst sensing and afibrinogenemii, etc.) and other krovotecheniyah associated with reduced maintenance fibrinogena blood.
In order to apply preventive Fibrin in preparation for the operation patients with gipofibrinogenemiey.
Enter solution fibrinogena in vein for the infusion through the filter, kapelno. Preparation ex tempor e dissolve in water for injection, podogretoy to a temperature of up to + 25 + 35 'S; Water quantity indicated on the label (in the vial). The solution should be used no later than 1 hour after cooking. The dose depends on the testimony of the drug, ranging from 0.8 to 8, 0 g or more. The average dose is typically 2 - 4 d.
Fibrin contraindications to predtromboticheskih condition, arrhythmia different etiology, high blood youngest, myocardial heart attack.
Form release: in the hermetically ukuporennyh glass vials capacity of 250 or 500 ml, respectively, containing 1 g (0.2 g # 1) or 2 g (1, 9 g # 0,1) koaguliruemogo protein (fibrinogena). By gm vial for injection system attached to the filter.
Storage: at the temperature of up to + 2 + 10 'C in dry, sheltered from the world scene. Storage products at a temperature above + 10 'C is fibrinogena topics.
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