Fluoxetine (fluoxetine)


FLUOKSETIN (Fluoxetine) *. # -N- Methyl West phenyl (Paralympic three ftormetil) fenoksipropilamina hydrochloride.
     White or almost white crystalline powder, it is difficult to dissolve in water.
     Synonyms: Prozak, Prosac.
     Is active inhibitor reverse takeover serotonin nerve end, little impact on the capture and noradrenalina dofamina. Poor operating on holinergicheskie and N-1 gistaminovye receptors.
     Apply with different types of depression (especially depression, accompanied by fear). Normal adult dose of 20 mg per day (inside). In a few weeks, increasing the dose of 20 mg per day. The maximum daily dose is 80 mg. Persons aged and elderly age appoint dose of no more than 60 mg per day.
     With a single admission (20 mg), taken morning, with double-morning and afternoon.
     The product is well absorbed. The maximum concentration in plasma blood through a 4 - 8 hours after administration of the interior, polususchestvovaniya period of about three days. Report the form of the active metabolite (desmetil Fluoxetine) for 1 week.
     The entrenched therapeutic effect observed after 1 to 4 weeks after the start of treatment.
     The product is usually well tolerated by. Because of the weak antiholinergicheskim of Constipation is relatively rare, drought in the mouth (compared to amitriptyline and other antidepressant drugs). May cause drowsiness, headache, nausea, vomiting, loss of appetite (a anoreksigennym action).
     Do not use drugs while MAO inhibitors, and not before 14 days after their admission. No alcohol intake.
     Form release: capsules containing 20 mg (0.02 g) Fluoxetine.

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