FLUPENTIKSOL (Flupentixol).

     4-[3-[2 - (Triftormetil) -9H- tioksanten-9- iliden] propyl] -1 - piperazinetanol.

     Synonym: Flyuanksol, Fluancsol.

     Has antipsychotic, anksioliticheskim, antidepressant and mild sedative effect.

     Is blokatorom central dofaminovyh receptors.

     After receiving inside well absorbed, Cmax is 3-6 h; T? 35 h (for dekanoata-3 weeks); biotransformation exposed in the liver, appears in the form of metabolites through the kidneys and partial bowel.

     Apply: large doses of psychosis dominated hallucinations crazy, thinking violations and small - to depression, chronic disorders and psychosomatic disorders violations involving anxiety, asthenia and apathy.

      Assign inside. When psychosis initial daily dose of 0,005-0,015 grams (5-15 mg) 2-3 admission (up to 0.04 g / day), supporting-0,005-0,02 g (5-20 mg) 1 times a day-morning; in border states, 0,001 g (1 mg) one every day, if necessary, to increase the daily dose of 0,002-0,003 grams (2-3 mg).

     Using drugs often extrapyramidal disorder may arise insomnia or sleep, neuroleptic malignant syndrome, a violation of liver samples.

     The product contraindications in processing and hyperactivity.

     To designate caution when convulsant syndrome, chronic hepatitis and cardiovascular disease.

     Increases effect of alcohol, barbiturates and other drugs, ugnetayuschih TSNS reduces - levodopa.

     Method of production: tablets (Bean) to 0.0005 and 0.001 g (0.5 and 1 mg) (N.50), and 0,005 g (5 mg) flupentiksola hydrochloride (N.100); 10% solution (drops) flupentiksola dihydrochloride in vials of 10 ml.

     There is also a product of prolonged flupentiksola Fluphenazine. Assign intramuscularly on 0,05-0,2 g (50-200 mg), 1 time every 2-4 weeks, after kupirovaniya STDs acute dose to reduce 0,02-0,2 g (20-200 g).

     Form release: 2% and 10% oil vnutrimyshechnogo solutions for the introduction of ampoule and 1 ml, 2% in the ampoule and 2 ml vials of 10 ml and 10% in 5 ml vials.

     Storage: List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines