Fluphenazine decanoate (fluphenazine decanoate)
FLUFENAZINA DEKANOAT (Fluphenazine decanoate). Triftormetil-10- 2 - (3-[1-(b-kaprinoiloksietil) - piperazinil-4]) - propyl - fenotiazin.
Synonyms: Liorodin- depot, Moditen- depot, Ftorfenazina Fluphenazine, Ftormenazin- depot, Moditen- depot, Modekeyt, Mirenil- ointment, Flunazol, Lyogen-depo, Lyoridin-depo, Lyogen-retard, Modecat, Moditen-depo, Fluphenazinum decanoate, Phthorphenazinum decanoate.
Heavy adjunct providing prolonged operation. Prolonged effect associated with changes in the chemical structure ftorfenazina (substantial balance kaprinovoy acid), which increases the relative molecular mass of the drug and gave it high NH. In a drug form (solution in oil) product after a single intramuscular injection, depending on the dose by 1 to 2 weeks or more. Long-term maintenance drugs in the body determines its high efficiency and especially therapeutic action. The product is most effective when nevrozopodobnyh and gallyutsinatornyh disorders.
Assign as adjunct to express antipsychotic action with a trigger and weak sedative effect, in different forms, schizophrenia, especially if stuporozno- katatonicheskih disorders in paranoidnyh state, with the passion of ongoing fear and weak during the process-dominated state of anxiety apaticheskih et al .
The product shows patients with schizophrenia during long-term disadvantage. In some cases, providing treatment for lack of other (neprolongirovannyh) neyrolepticheskih funds.
In connection with a long of convenience for patients, which is difficult brain function in the usual form. To a greater extent than usual (neprolongirovannye) products suitable for outpatient treatment and facilitate rehabilitation patients.
The product is widely used for relapse supportive therapy in schizophrenia. There is a need, however, to consider the following: despite the fact that the application of the drug have become rarer still not completely cure and prevent recurrence through long (about 5 years), a number of patients seen weakening of relapse, which raises the need for other antipsychotic drugs.
Apply ftorfenazin- Fluphenazine intramuscularly. Enter to 12, 5-25 mg, sometimes 50 mg (0.5 mL of 2 - 2, 5% solution) every 1 to 3 weeks. In therapeutically resistant cases paranoid schizophrenia entered 1 - 4 2 ml, 5% solution (25-100 mg) every 1 to 3 weeks.
In a possible drug phenomenon VGA, Akathisia, tremor-hand fingers, etc. In order to prevent these phenomena and kupirovaniya appoint Trihexyphenidyl holinoliticheskie ANTIPARKINSONISM or other drugs.
Form release: 2, 5% solution of oil in the ampoule and 1 ml (25 mg in 1 ampoule).
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