Glipizid (glipizide)


GLIPIZID (Glipizide). 1-Tsiklogeksil-3- [para-2- (5-metilpirazinkarboksamid) ethyl] phenyl] - sulphonyl] urea.
     Synonyms : Minidiab, Glibenese, Glucotrol, Glydiazinamide, Melizid, Menodiab, Mindiab, Minibetic, Minidiab, Minodiab.
     On the chemical structure and action is very close to glibenklamidu.
     Well absorbed. The maximum concentration in the blood is 1 to 2 h after administration. Is small half (3 to 4 h with 5-to 7 glibenklamida hour and 30-hour to 40 hlorpropamida). Quickly withdrawn from the body, hence the reduced risk of cumulation.
     Indications for use are the same as for other antidiabetics derivatives sulfonylureas (type II diabetes).
     Initial dose is typically 2, 5, 5 mg (1 / 2 - 1 tablet) per day, further increasing the dose of 1 / 2 to 1 pill to achieve optimal dose of support.
     The maximum dose of 30 mg (6 tablets) a day. Малые дозы принимают 1 раз в день, дозы свыше 15 мг - в 2 - 3 приема.
     Contraindications and precautions are the same as when applying glibenklamida, butamida.
     Product : pills to 0,005 grams (5 mg) in a package of 30 pieces.

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