GONADOTROPIN HORIONICHESKY (Gonadotropinum chorionicum).

     Synonym : Chorionic gonadotropin.

     Human chorionic gonadotropin for injection (Gonadotropinum chorionicum pro injectionibus). In producing sterile dried form. White or almost white powder; His nestoyki solutions; They were prepared just before use of isotonic sodium chloride solution.

     Biological activity determined by hormones. One of the units (ED) with the activity of 0.1 mg standard powder chorionic gonadotropina.

     Abroad chorionic hormone drugs are produced under the title Horiogonin, Antelobine, Choriogoninum, Entromone, Follutein, Gonabion and others.

     Applied on lowering the sex glands function in men and women, resulting from violation of the hypothalamus and pituitary. The drug shows patients with mezhutochno - hypophyseal insufficiency (Simmonds illness, syndrome Schiena, pangipopituitarizm any etiology, adipozogenitalnaya dystrophy, hypophyseal dwarfism with the phenomena of sexual infantilism, gipogonadotropny with hypogonadism phenomena evnuhoidizma) anovulyatornoy ovarian dysfunction and related infertility, sexually latest development in preserving and threatening abortion in the first trimester of pregnancy, dysfunctional uterine krovotecheniyah among women of childbearing age; while bilateral kriptorhizme children, as well as in the case of one kriptorhizme after prompt treatment with signs evnuhoidizma. The drug is used for the purpose of differential diagnosis of primary and secondary hypogonadism in men.

     Human chorionic gonadotropin appointed by intramuscular injection in doses of 500 to 3000 ED / day (depending on the nature and severity of illness, age of the patient).

     Men are 2 to 3 times a week for 4 weeks training with intervals 4-6 weeks. To 3-6 rates for 6-12 months.

     Women with anovulyatornyh cycles with a high level of estrogen to enter from the 10 - 12-day cycle for 3000 ED 2 - 3 times with intervals 2 - 3 days or 1500 ED 6 to 7 times a day.

     When treating mezhutochno- hypophyseal insufficiency Human chorionic gonadotropin recommended after a preliminary application (in the first phase of the cycle) follikulostimuliruyuschego hormone.

     In hypophyseal nanizme imposed on 600-1000 ED 1 to 2 times a week for 1 - 2 months repeat courses. In kriptorhizme children treated most effectively under the age of 10 years imposed on 500-1000 ED (aged 10 - 14 years - 1500 ED) two times a week for 4 to 6 weeks re-training or a period of 4 - 5 mon.

     Possible side effects allergic reactions; Too eggs in the inguinal canal, which could prevent their further lowering; When a drug overdose in women with ovarian giperstimulyatsiya can increase their size.

     Human chorionic gonadotropin contraindicated in inflammatory diseases and tumors sexual sphere.

     Not too long encouraged the use of the drug because of the potential of antibodies and suppressing gonadotropnoy pituitary function.

     Product : in the hermetically ukuporennyh bottles of 500; 1000; 1500 and 2000 ED in the form of dried powders with applications to each bottle sealed with the solvent.

     Storage : in the dark place at a temperature no higher than+ 20  C.

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