GREPAFLOKSATSIN (Grepafloxacin).

     (±) -1 - Tsiklopropil-6- fluorine-1, 4-digidro-5- metil-7- (3-methyl piperazinil) -4 - oxo hinolinkarbonovaya acid.

     Synonym : Raksar, Raxar.

     By chemically very similar to ciprofloxacin and moksifloksatsinu. As these drugs is in a molecule tsiklopropilnuyu group. From ciprofloxacin differs only in a molecule containing two methyl groups, but has a more lasting effect.

     On spectrum antimicrobial action close to tsiproflosatsinu.

     Quickly and completely absorbed in the digestive tract, bioavailability of approximately 70%, T? after repeated admission), 10-13 h; easy to move into the organs and tissues; biotransformation exposed in the liver, presented with urine and bile.

     Applied with pneumonia (including atypical), aggravated chronic bronchitis, uncomplicated gonorrhea and hlamidioznyh Urethritis and tservitsite.

     Assign inside of 0,4-0,6 1 g once a day during 7-10 days, gonorrhea, 0.4 g once.

     Possible side effects and contraindications are basically the same as that pefloksatsina.

     Product : pills to 0.4 g (N.5, 7) and 0.6 g (N 5).

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines