GUANFATSIN (Guanfacine) *. (2, 6-Dihlorfenilatsetil) - Guanidine.

     Available as hydrochloride.

     Synonyms : Estulik, Estulic [name drug companies "a nd on the S z" (Switzerland), Guanfacine hydrochloride, Hipertensal, Tenex.

     On chemical structure and the mechanism of close to guanfatsin klofelinu. Like klofelinu, it is a stimulant (agonist), a central 2-adrenoreceptor, reduces the flow sympathetic impulses from the central nervous system.

     Applied for the treatment of hypertension. The drug is well absorbed from the gastrointestinal tract, little binds blood plasma proteins. Peak plasma concentrations observed after 3 h after administration, the half of 13-14 hrs (up to 18 h). This has allowed for the preparation of one every day.

     Write mainly with urine.

     Assign guanfatsin as antihypertensive agents for treating various forms of hypertensive renal disease and hypertension.

     Adults usually take a daily dose of 1 mg (or 0.5 mg) one time at night (because of disturbances caused by drug and the possibility of abrupt AD). With insufficient daily dose gradually increased to 2 mg (also 1 reception), in rare cases, up to 3 mg, adding no more than 0.5 to 1, O mg and not more than one per week.

     If necessary, you can assign Diuretics.

     Possible side effects, precautions and contraindications are the same as for klofelina.

     The drug gradually abolished.

     Due to the lack of experience of the drug in children should not be appointed to the age of 12.

     Product : pills to 0.5; 1 and 2 mg in packages of 30 or 100 pieces.

     Storage : in the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines