GEKSENAL (Hexenalum).

     1,5-Dimetil-5- (tsiklogeksen-1- mud) - barbiturate sodium.

     Synonyms : Cyclobarbitalum solubile, Endodorm, Enhexymal natrium, Enimalum natrium, Eudorm, Evipal sodium, Evipal soluble, Evipan sodium, Hexanastab, Hexobarbitalum natricum, Hexobarital sodium, Hexobaritone soluble, Methylhexabarbital soluble, Methylhexobital, Narconat, Narcosan soluble, Noctivane, Novopan et al .

     White penoobraznaya mass. At the air under the influence of carbonic acid degrades. Gigroskopichen.

     Very easily soluble in water and alcohol, virtually nerastvorim broadcasts. Aqueous solutions geksenala fragile, easily gidrolizuyutsya, decompose when sterilization. Solutions are giving in terms of isotonic sodium chloride solution or sterile water for injection immediately before use. Store solutions can be no more than an hour. By applying suitable only totally transparent solutions.

     Geksenal provides sleeping pills and narcotic effects.

     Applied geksenal intravenous narcosis. After intravenous aqueous geksenala quickly comes to drugs, which continues after a single dose of about ZO mines.

     In plasma water-soluble form of the drug is rapidly becoming neionizirovannuyu lipofilnuyu form easily diffuse through the blood-brain barrier.

     In connection with the depressing effect on the respiratory and sosudodvigatelny points to a prolonged intravenous narcosis geksenalom not normally resort, it is used primarily for induction narcosis, combined with nitrous oxide, ftorotanom, air or other means used for the core narcosis.

     As a means of self narcosis geksenal used primarily in short vnepolostnyh operations (not more than 15 or 20 minutes) and endoscopy. Geksenalovy anaesthesia can be combined with a local anaesthetic.

     Enter geksenal intravenous slowly, usually at the rate of 1 ml per minute. The toxic effects (circulatory and respiratory depression) increases with the increase of speed and concentration of the solution geksenala (and other barbiturates). For narcosis usually about a 1 - 2% solution geksenala (some 2.5 to 5% solution). Initially introduced 1 - 2 ml, and in the absence during the 30-40 side effects from introducing additional solution. Laboratory dose depending on the type of intervention, the overall condition of the patient and others at 0.5-0.7 g of the drug (8-10 mg / kg).

     A weakened patients, in patients with cardiovascular disease and in children using 1% solution.

     As preparation, less activates vagusnye reaction than tiobarbituraty (tiopenantal- sodium), geksenal often used for the introduction of anaesthesia with tomography. Enter in the veins (within 2 to 3 minutes) 1 - 2% solution at 400-600 mg.

     Higher-time (she daily) dose geksenala adult non-1 yr

     Before anaesthesia geksenalom patient impose atropine (or metacin) for the prevention of side effects associated with the initiation of wandering nerve.

     For edema mental institution imposed geksenal in Vein : from 2 to 10 ml of 5% or 10% solution, depending on the patient. In acute alcoholic psychosis (and other serious violations of the psyche) recommended the introduction geksenala (7 - 10% 10 ml solution intravenously) to complement the introduction of intramuscular aminazina (4-5 ml of 2.5% solution).

     Geksenal contraindicated in violation of liver function (primarily drug is metabolized in the liver), as well as renal excretory function in sepsis, inflammatory diseases lying in state lihoradochyh, oxygen deficiency, while dramatically expressed violations bloodstream. In intussusception is not recommended geksenalom anaesthesia, as it hampers motor activity intestines.

     Not recommended geksenalovy anaesthesia in section deliveries, because it passes through the placental barrier and can cause asphyxia fruit.

     When complications associated with the geksenala (respiratory depression and heart disorder) can be applied Bemegride. Enter as intravenous calcium chloride (10 ml 10% solution).

     Product : 1 g of glass bottles, rubber hermetically eakrytyh congestion, obzhatymi aluminum caps.

     Storage : List B. In a dry, cool, the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines