Vitamin 125190 (holekaltsiferol) - aqueous solution


VITAMIN D3 (holekaltsiferol) aqueous solution.
     Synonym : Kolekaltsiferol, Colecalciferol
     Vitamins D and ergocalciferol holekaltsiferol are fat-soluble substances used in oil solutions; They are also on the index tablets. В последнее время разработана водорастворимая лекарственная форма холекальциферола (витамин Д3), удобная для перорального применения и высокоэффективная в отношении профилактики и лечения рахита и других патологических состояний, связанных с дефицитом в организме витамина Д.
     When administered drug is rapidly absorbed (5 times faster solutions oil), a high concentration of vitamin D in the body and has a prolonged effect.
     Терапевтический эффект препарата, как и действие эндогенных витаминов Д (эргокальциферола и холекальциферола), обусловлен регуляцией метаболизма кальция и фосфатов. Vitamin D3 helps absorption of calcium and phosphate from the intestines, regulates their participation in bone calcification, slowing down of calcium and phosphorus ions from the body. Регулирующим влиянием на метаболизм ионов кальция и фосфора объясняются и другие особенности действия препарата: регулирование про­цессов нервного возбуждения, тонуса мускулатуры, свертывания крови и др. (см. Препараты кальция и средства для лечения остеопороза).
     Applied vitamin D3 (holekaltsiferol) aqueous solution with the following statement : prevention and treatment of rickets; Gipokaltsiemicheskaya Tetany; Gipoparatireoz; Disorder and osteoporosis, including the prevention and treatment of osteoporosis associated with hormonal irregularities among women in menopause.
     Assign inwards in the form of drops.
     For post-specific prevention of rickets among newborns healthy children lowest dose of 400-500 IU (1 drop) a day. This dose applied from 3-4 weeks of age in the autumn-winter and spring in the first two years of life, according to the condition of the child and risk factors of disease. Children at risk for rickets daily designate 1000 IU (2 drops) at the same time. When I insufficiency of applying for 400-1000 IU (1-2 drops) daily, starting with 10-14 day life in the first two years (excluding summer months), with the degree of prematurity II-1000-2000 IU ( 2-4 drops) daily in the first year of life and 500-1000 IU (1-2 drops) in the second year of life (excluding summer months).
     To treat rickets is usually 2000-5000 IU (4-10 drops) daily for 30-45 days and then transferred to the supporting dose (500 IU) 1 every day for two years and in the winter in the third year of life ( 5000 IU dose used only expressed in bone changes). After 3 months after the end of the 1 st rate for children at risk for relapse rate of re-treatment (for 2000-5000 IU) for 3 to 4 weeks (except for the summer months).
     When dispensing drugs well tolerated. However, overdose and too long-term use may develop gipervitaminoza D3 (loss of appetite, constipation, nausea, vomiting; Headaches, muscle, joint aches; Poliuriya; Weight loss and other side effects).
     Please note that vitamin Dz crosses the placental barrier and milk in nursing mothers.
     Like other drugs holekaltsiferola, the water-soluble form is not suitable for high levels of calcium in the blood and urine, while calcium and kidney stones, kidney failure, sarcoidosis.
     It should not be used in conjunction with HP rich in high doses.
     In all cases, the discovery of hypersensitivity to the drug further his admission stop.
     FORM OUTPUT : solution for the reception inside (15,000 IU / ml; IU 500 in 1 drop) in flakonah- looks for 10 ml.
     STORAGE : in a cool, the dark spot.

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