GIGRONY (Hygronium). ~ Dimetilaminoetilovogo-N-methyl-ester pirrolidinkarbonovoy diyodmetilat acid.

     Synonym : Trepirium iodide.

     White or white to slightly yellowish sheen crystalline powder. Very easily soluble in water. In water solutions fragile.

     Refers to bischetvertichnym ammonium compounds, a structure is similar to dimekolinom.

     Provides short ganglioblokiruyuschee effect, and therefore suitable for use in anaesthetics practice run for hypotension.

     Applied intravenous drip of 0.1% in the isotonic solution (0.9%) solution of sodium chloride. Started with 70-100 drops per minute and after the necessary anti-hypertensive effect reduces the number drops to 30 to 40 minutes. Day c sport comes after 2 to 3 minutes, and the original AD restored after 10 to 15 min after injection. In a stroke or a (40-80 mg of 3 - 5 ml isotonic sodium chloride solution) anti-hypertensive effect continues 10 - 15 min. In cases of excessive downward AD apply Levophed or mezaton.

     Gigrony as other ganglioblokatory, can be used in obstetric practice with nephropathy in pregnant women, eclampsia. There is evidence of the successful use of a drug for edema gipertonichesnih crises (40-80 mg of 15 - 20 ml isotonic sodium chloride solution intravenously slowly within 7 to 10 minutes).

     Product : in vials or ampoules with a capacity of 10 ml, containing 0.1 g gigroniya. Just before dissolving drug use.

     Storage : List B. In the dark spot.

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