Imipenem (imipenem)


IMIPENEM (Imipenem).
     N-Formimidoiltienamitsin or (5S, 6R) -3-[[2 - (formimidoilaminoetil) thio] -6 [R] -1 - hydroxyethyl] okso-1- azabitsiklo -7-[3.2.0] - gept- en-2- 2-carboxylic acid.
     Synonym : Imipemide.
     Imipen is a broad-spectrum antibiotic. Effective against gram and gram microorganisms. Has a strong bactericidal effect. Resistant to b-laktamazy gram of bacteria. Effective at R s ud on m on nas t ruginos but Saratia, E nterobacter resistant to most b-laktamnyh antibiotics.
     For medical use of drugs produced combined with imipenem in conjunction with the specific enzyme inhibitor digidropeptidazy kidney-tsilastatinom. This combination of slowing metabolism imipenem kidney and increases neizmenennogoantibiotika concentrations in the kidneys and urinary tract.
     This drug combination is known as "Tienam.

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