IMIFOS (Imiphosum).

     Dietilenimid 2-methyl tiazolido-3- phosphoric acid.

     Synonyms : Markofan, Marcophan.

     The white crystalline powder. Very easily soluble in water and alcohol.

     Applied for patients eritremiey deployed in the stage of the disease, leaking from an enlarged spleen and pantsitozom.

     Enter intravenously or intramuscularly to 0.05 g (50 mg) usually in a day. With high sensitivity and rapid decrease of leukocyte count in the blood, increasing the intervals between injections to 2 to 4 days. The total dose imifosa to treatment averaged 0.5, 0.65 g. In case of recidivism can be repeated courses, but no earlier than 6 months after the first course; Drug nominated for the above amounts.

     In applying imifosa can develop radiation and thrombocytopenia. If necessary, replace the preparation and appoint leykopoeza stimulants, blood transfusions or leykotsitnoy and trombotsitnoy estate.

     During treatment imifosom need at least two times a week to study blood; After treatment blood examines one every 10 to 15 days during the three months.

     Imifos contraindications patients with severe exhaustion and anemia, radiation, thrombocytopenia.

     U of patients there refrakternost to drugs.

     Product : in sealed ampoules or vials containing 0.05 g (50 mg) imifosa. By dissolving drug for 10-20 ml isotonic sodium chloride solution immediately before use.

     Storage : List A. In the dark place at a temperature of not more than + 5 C.

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