INGITRIL (Ingitrilum).

     The drug, derived from the lungs of cattle.

     Dried powder cream or white with serovatozheltym shade color. The easily soluble in water and isotonic sodium chloride solution.

     Like pantripinu ingibiruet active proteolytic enzymes, reduces blood fibrinoliticheskuyu activity.

     Drug activity determined to reduce the activity of trypsin and express in ED; 1 g product contains at least 550 ED.

     Applied for the treatment of acute pancreatitis, exacerbations of chronic pancreatitis and other evidence of a decline in active and fibrinoliticheskih proteolytic enzymes.

     Applied intravenous (struyno drip). In acute pancreatitis preferably drip a drug to ensure smooth flow of the daily rate of 200 ED for the first day. Ingitril add in solutions imposed by the patient to compensate for the water loss, detoxification, etc., or dissolve the desired dose of 500-1000 ml isotonic sodium chloride solution.

     In cases of acute pancreatitis complicated, the purpose of the above dose of intravenously injecting drug concentrated solution (100 ED 10-20 ml isotonic sodium chloride solution). Then the daily dose ingitrila increase to 300 ED. In the next 2-6 days preparation appointed to the same dose, and with signs of therapeutic effect of the daily dose can be reduced to 150-100 ED. After cupping pain, vomiting, removal of peritoneal events disappearance paresis bowel, ending tachycardia, normalization of blood and urine amylase, ingitril within 3 to 4 days to introduce drip for 60 hours a day in the ED. If necessary to increase the dose to 100-150 ED in the day and continue treatment even 2-6 days. Admission drug stop, as soon as a permanent improvement. Heading ingitrila dose for the treatment of acute pancreatitis ranges from 600 to 5000 ED.

     Patients, operated in an artificial blood ingitril nominated for the prevention and treatment fibrinoliticheskih bleeding, as well as for the prevention and treatment of pancreatitis, often complicating operations. Starting with slow inkjet imposing 100-200 ED ingitrila (10-20 ml isotonic sodium chloride solution), then injected drip ED 200 per day during the first 3 days post-period.

     When gastrointestinal and other krovotecheniyah involving fibrinolysis, ingitril designate dose intravenous drip in ED 300 a day to stop the bleeding or normalization fibrinoliticheskoy activity.

     When pancreatic and high tonkokishechnyh disabilities, ingitril use local dose of 100 ED. The agent then dissolve in isotonic solution of sodium chloride or other solvents (liquid novocaine, lidocaine, glucose), enough for around-the-clock slow drip of a fistula.

     Patients with Burns shock and severe burn toxaemia, ingitril imposed for 5 to 7 days at 140-200 ED daily intravenous drip at the speed of 40-60 drops per minute. Allowed dissolution ingitrila correct dose of 200 ml of 0.1% solution of novocaine.

     During treatment ingitrilom could experience allergic reactions in the form of urticaria, easily kupiruemye antihistamines substances.

     The use of drugs contraindicated in cases involving high blood coagulation, and in patients who have previously been neperenosimost ingitrila.

     Product : 15 and 20 ED in vials with 5 ml, ukuporennyh rubber mixing with metal caps.

     Storage : dry, the dark place at a temperature of not more than + 20 'S.

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