LIZOAMIDAZA. (Lysoamidasa).

     Proteolytic enzyme, produtsiruemy bacterial culture from the family of R s udomonodaceae.

     Dried powder or porous mass of grey-brown shade of color. Little is soluble in water.

     Drug activity is expressed in units of proteases (PE). 1 mg product contains at least 0.7 PE.

     Lizoamidaza also bakterioliticheskoe effect. Bakterioliticheskaya (political) activity reflected in the LE.

     Lizoamidaza as proteolytic product helps cleanse wounds from the surgery necrotic masses accelerating fresh granulyatsy and improve the environment for healing.

     As bakterioliticheskoe vehicle preparation can destroy the cell wall of gram bacteria : staphylococcus, streptococcal korinebaktery and meningokokkov, gonokokkov and others.

     Applied adults for the treatment of burns and wounds festering for treatment of chronic necrotic masses, accelerate the establishment of fresh granulyatsy and healing. Assign with chronic inflammatory diseases of the skin (folliculitis, abrasions and other forms piodermy), with mastitis and endometritis, gum disease, stomatitis, pulpitah, peridontitis, wounding, disease mucous membranes of the mouth, etc., as well as for the treatment of angina and rescue direction .

     Local applied in the form of solutions in 0.01 M sodium phosphate buffer (pH 8, 0) in concentrations 5 PE (LE 50) in 1 ml; PE 1910 (LE 100) in 1 ml; PE 1925 (LE 250) 1 ml.

     With investments wounds, chronic inflammatory skin disease, mastitis and burns, apply lizoamidazy applications. Pre handle wounds, then swelling solution lizoamidazy gauze moistened towels and placed them on the wound surface of waterproof bandage. Dressed as drying change 1 to 2 times daily. Depending on the type and amount of surface area. the daily dose is 250-500-PE (2500-5000 LE) and can be extended. The course of treatment exhibition wounds 7 - 10 days, burning 6 - 7 days. With deep wounds hot towels or foam sponge soaked abundantly lizoamidazoy, gifs fill Wound move. With Irrigator towels or sponges moistened 4 - 5 times a day. Change towels to every 3 to 4 days. The daily dose is 100-150 PE (1000-1500 LE).

     When endometritis lizoamidazoy to irrigate 1 to 2 times daily. The daily dose is 150-400 PE (1500-4000 LE). The course of treatment for 5 to 7 days.

     In dental practices used applications and oral rinse product. Rinse produce two times a day for 10 minutes, taking advantage of 50-60 ml (100-300 PE; 1000-3000 LE) solution. The course of treatment is 5 to 7 days. Before application, the mucous membrane process sodium phosphate buffer solution. Application in a 30-60 minutes; During the procedure change tampons 4 - 5 times.

     When rescue bed using applications lizoamidazy solution to the mucous membrane of the nose for 10 minutes one time a day. Daily dose of 5-20 PE (50-200 LE). The course of treatment 2 to 3 days.

     In applying lizoamidazy may be feeling light burning, which is taking place spontaneously.

     Product : dried in a 50 PE, and at least LE 500 or 100 PE and at least 1000 LE in vials, as well as 10000 PE and at least LE 100,000 in glass bottles. In preparation prilagaeteya phosphate buffer solution (0.01 mol / l) in 10 ml ampoules or bottles of 450 ml, for the dissolution lizoamidazy.

     Storage : dry, the dark place at a temperature of not more than + 10 'C.

Materials allowed to copy only with the active hyperlink to the handbook of medicines