MEKLOZIN (Meclozine).

     1-[(4-Hlorfenil) fenilmetil] -4 - (3-methylphenyl) methyl] piperazine.

     Synonym : Bonin, Bonine.

     Powder white and yellow. Poor soluble in water, soluble in alcohol and dichloromethane.

     On the chemical structure is similar to tsetirizinom (see).

     N1- gistaminovyh receptor blockers. Has weak antiholinergicheskimi properties. Has protivorvotnoe effect.

     Applied to prevent palpitations and nausea, vomiting, dizziness (including sea and air sickness, Menera syndrome), as well as an immediate allergic reaction type.

     Assign inside of 0,025-0,1 g (25-100 mg) a day (a few tricks); When motion for 0,025-0,05 g (25-50 mg) for 1 hour prior to the trip, while Ray illness in the same dose for 2-12 h before irradiation.

     Possible side effects : drowsiness, weakness, dry mouth, rarely fog-view.

     The drug is contraindicated in pregnancy and up to the age of 12 years.

     Be wary designate patients with glaucoma and isolationist prostate gland.

     Enhance of barbiturates, tranquilizers, sedatives, alcohol.

     Product : pills (including chewing) to 0,025 g (25 mg).

Materials allowed to copy only with the active hyperlink to the handbook of medicines