MELATONIN (Melatonin).

     N-[2 - (5 - 1 H-Metoksi indol-5- mud) ethyl] atsetilamid or N-atsetil-5- metoksitriptamin.

     Synonyms : Melaksen, Melapur, Melaton, Yukalin, Eucalin, Melapur, Melatonum, Melaxen and others.

     Powder. Mg in water and alcohol.

     By chemically very similar to serotonin (5-gidroksitriptaminu) and meksaminu (an O-and N-metilirovannym atsetilirovannym derivative serotonin).

     This endogenous compounds, produtsiruemoe epiphysis (pineal gland) brain.

    Physiological role of melatonin is not enough. He is believed to have played a role "synchronizer" biological functions (sleep phases, tsirkadnyh exchange processes, immune response, etc.). There is evidence of anti-and adaptogennoy activity.

     Melatonin "name" associated with detected in the experiment with frogs ability substances stimulate and reinforce the functions melanoforov skin pigmentation. Under the influence of the ambient light changes the speed of endogenous melatonin biosynthesis.

     Melatonin obtained by synthetic, and recent attempts to use it as an LS. Proposed regulations for the use of melatonin rhythm of sleep, especially if it fails to change time zone (during long-distance), and other disorders of sleep cycle; As adaptogennogo funds at higher loads on the body and in other states. An array of therapeutic effects of melatonin is not defined. In some countries it is recommended as a food additive.

     Assign inside (mostly at night). Normal recommended dose of 0,003 grams (3 mg).

     The maximum daily dose of 0,006 grams (6 mg).

     Possible side effects : drowsiness morning, swelling.

     Melatonin is not suitable for violations expressed kidney function, autoimmune diseases, leukemia, lymphoma, pregnancy, breast-feeding.

     Enhance effects of drugs, oppressive central nervous system.

     Product : pills to 0,003 g (3 mg) (N 2, 6, 12, 24, 30, 60).

     Issued dosage forms (capsules, tablets), containing melatonin along with other LS.

     Yukalin-pill on 0,003 grams (3 mg) of melatonin, as proposed adaptogene; Pills to 0,003 g 0,001 g of melatonin and valerian root powder as sleeping pills.

     Apik- melatonin tablets, 0,003 grams of melatonin and 0.01 g pyridoxine (vitamin B6).

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