Meterazin (metherazinum)
METERAZIN (Metherazinum). Hlor-10- 2-[3-(1-metilpiperazinil-4) - propyl] - fenotiazina dimaleat.
Synonyms : Chlormeprazine, Chlorperazin, Compazine, Dicopal, Nipodal, Novamin, Prochlorpemazine, Prochlorperazini maleas, Prochlorperazine maleate, Stemetil, Temetil and others.
White with a slightly yellowish sheen or light cream crystalline powder. Almost nerastvorim in water, very little is soluble in alcohol. In light redder.
By building close to aminazinu; In a different side chain piperazinovogo nucleus.
Like other piperazinovym derivative fenotiazina (etaperazin, triftazin etc.), meterazin weakens the problem symptoms, delirium and hallucinations; However, having activator (catalyst, energeziruyuschee) effect.
Applied for patients schizophrenia and other psychoses involyutsionnymi dominated in the clinical picture of weakness, apathy, Pichinde events substuporoznogo and stuporoznogo states.
Assign inside after eating from 0.0125, 0,025 grams (12, 5-25 mg) per day and gradually increasing the dose to 12, 5 to 25 mg per day to a daily dose of 0,15 - 0,3 g ( sometimes up to 0.4 g). Length Course 2 - 3 months and then gradually reduce the dose, dose individually selecting supportive.
Application meterazina in relatively high doses can exacerbate psychosis, insomnia, tachycardia. Large doses often provoke zkstrapiramidnyh development disorders, psoriasis. In long-term care can develop granulotsitopeniya.
Product : pills to 0,005 grams (5 mg) and 0,025 g (25 mg), coated in glass banks to 50,100 and 250 pieces.
Storage : List B. In the dark spot.
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Materials allowed to copy only with the active hyperlink to the handbook of medicines
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