METOKSIFLURAN (Methoxyfluranum) 1 1-(Diftor-2, 2 - dichloro-1 metoksietan)

     Synonyms : Ingalan, Pentran, Inhalanum, Methofluranum, Metofane, Penthrane, Pentran.

     Colorless transparent liquid fly to a specific fruity smell. Density 1.42. The boiling point of 105 C. At room temperature and the concentration used for narcosis, does not explode and ignite.

     Penthrane is a powerful drug of abuse and more intense than Halothane and broadcasts. Stop consciousness and surgical stage narcosis occurred at concentrations of 1,5-2. %, And to maintain required 0,5-0,8 of narcosis. inhalable% in the mixture. Anaesthesia is, but slowly, it is expressed in the initiation phase; Awakening after a mixture occurs in 15-60 minutes narkoznaya depression completely passes through 2 - 3 hours

     Due to the slow onset of effect and longest stage of proceedings Penthrane used primarily not for the self narcosis, and when combined with nitrogen oxide, barbiturates, muscle Ward. Usually beginning with the induction barbituratom narcosis, and then apply for narcosis mixture containing 0,5-1 on. metoksiflurana% in combination with nitrous oxide and oxygen (1:1).

     Anaesthesia metoksifluranom can hold open, semi, and semi-closed system, but most safely use apparatus with a special evaporator away from circulation system.

     Penthrane is prolonged analgesia, continued after the restoration of consciousness. The drug increases the sensitivity of catecholamines attack, but to a lesser extent than cyclopropane, Halothane.

     Side effects metoksiflurana basically similar to any ftorotana. Unlike last Penthrane is relaxing muscles uterus and has little impact on reducing the uterus during childbirth. In connection with this, and the activity analgeziruyuschey Penthrane used in obstetric practices (relatively low concentrations). It can be applied through Analgizery.

     Please note that Penthrane can impair kidney function : it reduces renal blood flow, klubochkovuyu filtering, mocheotdelenie. His relatively rarely used for a long narcosis.

     Indications are the same as for ftorotana (except for the influence ftorotana relaxing muscles in the uterus).

     Product : sklyankah in 10 and 20 ml.

     Storage : List B. In the dark spot.

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