METILENOVY BLUE (Methylenum coeruleum).

     N, N, N ', N'Tetrametiltionina chloride.

     Synonyms : Metilenovaya blue, Methylenblau, Methylthionii chloridum.

     Dark green crystalline powder or dark green with bronze crystals shine. It is soluble in water (1:30), little in alcohol. Aqueous solutions are blue.

     + Sterilized at temperatures of 100 C for 30 min.

     External applied as a means of antisepsis with burns, piodermii, tinea, etc; Use 1 to 3% alcohol solution. In anesthetic, filter, etc. wash cavity aqueous solutions of 1:5000 (0.02%).

     Inside appointed earlier methylene blue with anesthetic, and get other inflammatory diseases of urinary-adult for the 0.1 g 3 - 4 times a day, the children - an estimated 0,005 - 0.01 grams for each year of life in 3 - 4 admission .

     Vydelyayas with urine, drug stains in the blue, and therefore it is sometimes used to study the functional ability of the kidneys, but better results are obtained when applying for this purpose indigokarmina (see).

     Methylene blue is oxidation properties and reconstruction could play the role of acceptor and tycoon hydrogen ions in the body; This is based on its use as an antidote to some poisoning.

     Solutions metilenovogo give blue veins with cyanide poisoning, carbon oxide; Hydrogen sulphide : 50-100 ml of 1% aqueous metilenovogo blue or 1% solution metilenovogo blue in 25% glucose solution (hromosmon). Therapeutic effect in the administration of cyanide, based on the ability metilenovogo blue (the doses) transfer hemoglobin in metgemoglobin, svyazyvayuschiysya with cyanide.

     Entering metilenovogo blue veins in small doses (0.1, 0.15 ml of 1% solution of 1 kg of body weight), are returning metgemoglobina in hemoglobin. These properties are in drug poisoning metgemoglobinobrazuyuschimi poisons (nitrite, aniline and its derivatives, etc.).

     Method of issuance : powder; 1% aqueous solution of 1% alcohol solution; 1% solution metilenovogo blue in 25% glucose solution in capsules of 20 and 50 ml.

     Storage : powder-well ukuporennoy packaging keeps out of the light; Solutions, in the dark place.

     Rp. : Methyleni coerulei 0.5

     Spiritus aethylici 70% 50 ml

     M.D.S. For lubricating skin (with burns, rozhistom nerve, etc.)

     Rp. : Sol. Glucosae 25% 50 ml

     Methyleni coerulei 0.5

     D.t.d. N. 3 in ampull

     S. To give vein (in the administration of cyanide,)

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