Metronidazolgemisuktsinat (metronidazolhemisuccinas)


METRONIDAZOLGEMISUKTSINAT (Metronidazolhemisuccinas).
     Crystal Cream coloured powder. Little is soluble in water and alcohol. For medical applications issued in the form of a pharmaceutical form of the addition of N-metilglyukamina, sodium phosphate dvuzameschennogo and other fillers. There is dried powder or porous mass of white or yellowish sheen kremovatym, soluble in water and used for injection (metronidazolgemisuktsinat freeze for injection) for 0.5 grams and 0.3 grams per metronidazole (l Metronidazolhemisuccinas from ophilisatum 0,5 et 3 pro injectionibus 0).
     Coinciding with the chemotherapeutic effect of metronidazole. Applied to treat and prevent various forms of anaerobic infections, and severe forms of protozoal diseases (liver abscesses, lung, brain), Giardiasis. Has also radiosensibiliziruyuschee effect.
     Metronidazolgemisuktsinat injected (struyno drip). Introduction into the skin is not allowed.
     For inkjet first dissolve the contents of a bottle (0.5 g) in 10 ml of sterile water for injection, or isotonic sodium chloride solution, or 5% glucose solution, then the solution to throw 100 or 250 ml sodium chloride or glucose.
     In infectious diseases impose infuzionno (within 30 min 40), and with good endurance-struyno. Under the dose of 0.5 g for adults; Daily 1, G-1, 5 grams (2 to 3 times the 0.5 grams and an 8 h). The course of treatment 7 to 10 days. Usually, the only course.
     In ulcerative colitis disease Krona (see Salazosulfapiridin) are two courses (interval 2 months).
     The reception is possible allergic drug reaction, moderate radiation.
     Contraindications : pregnancy and breast-feeding.
     Product : in vials of 0.5 g (20 ml capacity) and 3 g (100 ml).
     Storage : List B. In the dark place at a temperature no higher than  + 10C.

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