MEKSAMIN (Mexaminum). 5-Metoksitriptamina hydrochloride.

     White with cream flavor crystalline powder.

     The easily soluble in water, it is difficult to alcohol.

     On chemical structure and pharmacological properties meksamin close to serotonin.

     Like serotonin, is narrowing the peripheral blood vessels, reducing the smooth muscles of internal organs. Has also sedative effect and makes a habit and analgetikov.

     An important feature is its meksamina radiozaschitnaya activity (see Tools for the treatment and prevention of radiation sickness). In the experiment, it reduces mortality of animals exposed to X-rays or gamma radiation, as well as high-energy protons. In the mechanism of radioprotective important, apparently caused by drug hypoxia in the "critical" of the brain, bone, spleen, etc., that may involve loss of these blood vessels.

     Patients who are subjected to radiotherapy on tumours, a reception inside meksamina phenomenon reduces radiation reaction.

     Applied for the prevention of radiation response when radiation therapy. Assign inside of 0.05 g (1 tablet) for 30 to 40 minutes before each session of radiation therapy. With good endurance dose can be increased to 0.1 g.

     The drug is usually well. In some cases, possible slight nausea, dizziness, pain in the area epigastralnoy less vomiting. Adverse events can be reduced with the use caffeine. In further bad Portability reception drug stop.

     Contraindications to express sclerosis and cerebral vascular heart disease, cardiac failure, bronchial asthma, kidney disease violation of the functions of pregnancy.

     Product : pills to 0.05 g (50 mg), coated.

     Storage : List B. In sklyankah dark glass in a dry, the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines